Design of an Implantable Device for Ocular Drug Delivery

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Design of an Implantable Device for Ocular Drug Delivery

Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide. There is an increasing need to develop devices for drug delivery to address ocular diseases. This study focuses on the design, simulation, and development of an impla...

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Drug Design Concept in Ocular Drug Delivery

Ocular administration of the drug is primarily associated with the need to treat ophthalmic diseases and is not regarded as a means for gaining systemic drug action. Major classes of drugs used are miotics, mydriatics/cyclopegics, anti-inflammatory, antiinfectives, surgical adjutants and diagnostics, which are all meant for local therapy. Systemic action by using eye as a portal is generally av...

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An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care Citation

We introduce the first implantable drug delivery system based on MEMS (MicroElectro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD 3 (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac r...

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An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care.

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD(3) (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac...

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Implantable MEMs for Drug Delivery

Figure 1: Photographs showing (A) top and bottom of the silicon microchip, and (B) a packaged device with wire-bonded connector We have developed an implantable silicon microelectromechanical system (MEMS) device for biomedical applications [1]. This device contains an array of wells that hermetically store its contents. Activation of the device electrochemically dissolves gold membranes coveri...

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ژورنال

عنوان ژورنال: Journal of Drug Delivery

سال: 2012

ISSN: 2090-3014,2090-3022

DOI: 10.1155/2012/527516